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Safety/Efficacy Study of Local Anesthetic Prior to Femoral Artery Sheath Removal

Not Applicable
Completed
Conditions
Syncope, Vasovagal
Pain Intensity
Registration Number
NCT00465439
Lead Sponsor
Hamilton Health Sciences Corporation
Brief Summary

This randomized controlled trial will examine the impact of local anesthetic on the frequency of vasovagal reactions and the patients perception of pain during femoral arterial sheath removal after percutaneous coronary intervention.

Detailed Description

Patients undergoing percutaneous coronary intervention(PCI) will be randomized to receive subcutaneous local anesthetic (Lidocaine 2% without epinephrine)or no local prior to removal of femoral arterial sheath. They will be assessed for vasovagal reactions and pain intensity during the sheath removal.The incidence of vasovagal reactions and pain intensity scores will be compared between the groups. 200 patients will be enrolled over the course of 2 months.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
78
Inclusion Criteria
  • Percutaneous Coronary Intervention
  • Femoral arterial sheath
Exclusion Criteria
  • Less than 18 years old
  • Emergency procedure
  • Transferred out of heart investigation unit prior to sheath removal
  • Radial or brachial sheath
  • Closure devise
  • Venous sheath insitu
  • Intra-aortic balloon pump insitu
  • Tranvenous pacing
  • Mechanical ventilation
  • Cognitive impairment
  • Unable to read English
  • Lidocaine allergy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Incidence of vasovagal reaction during femoral sheath removalDuring sheath removal
Pain intensity during femoral sheath removalDuring sheath removal
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Hamilton Health Science-Heart Investigation Unit

🇨🇦

Hamilton, Ontario, Canada

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