The exercise and gut bacteria study

Completed

• Conditions: Nutritional, Metabolic, Endocrine; Obesity

• Registration Number: ISRCTN91278516
• Lead Sponsor: niversity of Leicester

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11-30
• Last Update Posted: 16 October 2017

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 19

Inclusion Criteria

1. Caucasian Males
2. Aged 25-50 years inclusive
3. BMI 30-40kg/m2 inclusive
4. HbA1c less than 6.5%
5. Completion of an eligibility stress test and approval from an in house clinician according to our standard operating procedures
6. Able to speak and understand English

Exclusion Criteria

1. Unable to understand and speak English
2. Unable to provide written informed consent
3. Diagnosed with type 1 or 2 diabetes
4. Diagnosed with crohn’s disease, celiac disease or irritable bowel syndrome
5. Highly active individuals or individuals meeting current physical activity guidelines (self­report =2.5 hours per week)
Participants should not report exercising two or more times per week for 20minutes or longer over the past six months
6. Patients with orthopaedic limitations, motor neurone disease, stage II hypertension (systolic BP>160 and/or diastolic 
BP>100mmHg), cardiovascular disease (coronary artery disease, cardiomyopathy, heart failure, cor pulmonale, 
cardiac dysrhythmias, endocarditis, myocarditis, valvular heart disease, cerebrovascular disease, peripheral arterial 
disease, congenital heart disease and rheumatic heart disease), pulmonary disease (inflammatory lung disease, 
obstructive lung disease, chronic obstructive pulmonary disease, emphysema, cystic fibrosis, respiratory tract 
infections, pleural cavity disease, pulmonary vascular disease) renal disease or chair bound
7. Current smokers
8. Are currently on a calorie restricted/weight loss diet
9. Have changed their dietary habits in the past three months
10. Individuals who have used antibiotics or pre/probitoics in the past three months
11. Weight limit (due to operating scales): maximum 200kgs

Study & Design

• Study Type: Interventional
• Study Design: Not specified