Exercise effect on human intestinal bacteria
Not Applicable
Recruiting
- Conditions
- digestive system diseasesgastrointestinal microbiomeG06.755.375
- Registration Number
- RBR-299d6k
- Lead Sponsor
- Escola de Educação Física e Esporte da Universidade de São Paulo
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- Not specified
Inclusion Criteria
Young adults (18 and 35 years old); sedentary for at least six months; BMI between 18.5 and 29.9kg/m²
Exclusion Criteria
Those who ingested any antibiotics in the last three months; if they are vegan vegetarians or are following some kind of restrictive diet; if they have intolerance or allergy to any food; presence of chronic or acute diseases of the gastrointestinal tract and/or other chronic disease, such as dibetes or arterial hypertension; presenting disability and/or any other clinical complications that prevent the practice of physical exercise. Besides that, the lack of availability to participate in our training schedule and collections.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method It is expected that the aerobic continuous exercise with moderate intensity is able to cause positive changes on the intestinal microbiota in human quantitatively and qualitatively. The increased diversity of intestinal bacteria is associated with an improvement in intestinal health. Besides, it is expected that there will be a increase in butyrate concentration, a substance produced by some groups of bacteria, which is beneficial for the intestinal epithelium.
- Secondary Outcome Measures
Name Time Method Its is expected that the exercise improves the circulation of biochemical markers, such as, HDL-c, LDL-c, fasting blood glucose and triglycerides. Also, it is expected that volunteers of intervention group increase their fitness and aerobic capacity (VO2peak).