NCT00288652已完成2 期
[S,S]-Reboxetine Dose-Range Finding Trial: A 16-Week, Randomized, Double-Blind, Placebo And An Active Comparator Controlled, Multi-Center Trial Of [S,S]-Reboxetine In Patients With Postherpetic Neuralgia (PHN)
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- Pfizer
- 入组人数
- 280
- 试验地点
- 79
- 主要终点
- The numerical pain intensity rating scale is used to assess pain and a change from baseline in pain score for week 14 will be calculated
研究概览
简要总结
The purpose of this study is to determine the effectiveness of different doses of [S,S]-Reboxetine in the treatment of chronic pain following a shingles infection
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must have pain present for more than 3 months after the healing of shingles skin rash
- •Patients at screening must have a score >/=40 mm on the pain visual analogue scale
排除标准
- •Patients with significant renal and hepatic impairment
- •Patients with other severe pain, that may impair the self-assessment of the pain due to shingles
- •Patients with clinically abnormal electrocardiogram
结局指标
主要结局
The numerical pain intensity rating scale is used to assess pain and a change from baseline in pain score for week 14 will be calculated
次要结局
- - The mean endpoint (week 14) sleep interference score change from baseline - Analysis of the Medical Outcomes Study Sleep Scale - Analysis of the Patient Global Impression of Change - Analysis of the SF-36 Health Survey
研究者
研究点 (79)
Loading locations...
相似试验
已完成
1 期
Repeated Dosing Clinical Trial of HL151Rhinitis, Allergic, PerennialNCT02686294Hanlim Pharm. Co., Ltd.30
已完成
2 期
A 4-week Dose-Ranging, Dose-Interval, Efficacy, Safety and Tolerability Study of GSK961081 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)Pulmonary Disease, Chronic ObstructiveNCT01319019GlaxoSmithKline437
已完成
1 期
A Study to Evaluate Safety and Pharmacokinetics/Pharmacodynamics of Sustained Release(SR) ExenatideType 2 Diabetes MellitusNCT00964262Peptron, Inc.34
已完成
2 期
A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler (Puffer) in Adolescents and Adults Who Have Asthma That is Not Controlled by High Dose Inhaled Corticosteroid Asthma MedicationsAsthmaNCT01576718Teva Branded Pharmaceutical Products R&D, Inc.889
已完成
2 期
A Study in Pediatric Patients With Cystic Fibrosis Lung DiseaseCystic FibrosisNCT00130182Merck Sharp & Dohme LLC13