Study to assess the effectiveness of celiac plexus nerve block by means of ultrasound technique with the help of ultrasound contrast agent
Not Applicable
- Conditions
- Health Condition 1: C15-C26- Malignant neoplasms of digestive organs
- Registration Number
- CTRI/2022/06/043412
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Males or females with upper abdominal malignant tumours diagnosed by histopathology or imaging.
2. A score of more than 7 on a 10 point Visual Analog Scale (VAS) for abdominal pain.
3. Unresectable tumours.
Exclusion Criteria
1. Poor condition (unstable vitals)
2.Widely metastasizing tumour in peritoneum involving the celiac plexus and infiltrating abdominal wall/ peritoneum causing somatic pain.
3.Non-correctable coagulopathy and thrombocytopenia.
4. Massive ascites
5.Known allergic reaction to specific agents.
6.Uncontrolled hypertension
7.Recent MI or unstable angina.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Contrast enhanced ultrasound guided celiac plexus neurolysis alleviates pain due to upper abdominal cancer pain in 80% of patients who underwent the procedure.Timepoint: Pain status is assessed - immediately , on day 1 , 1 week , 1 month and 3 months after procedure using VAS (Visual Analogue Scale) score
- Secondary Outcome Measures
Name Time Method Degree of dispersion of neurolytic agent around aorta is directly related to level of pain relief.Timepoint: 3 months