Neither Pre-sleep Nor Post-exercise Protein Consumption Influences Resistance Exercise Training Adaptations in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 2
- 主要终点
- Muscle thickness
研究概览
简要总结
The goal of this clinical trial is to compare the effects of protein consumption before sleep or immediately after exercise during 12 weeks of resistance exercise training in older adults. The main questions it aims to answer are:
Are there differences in muscle growth or strength during 12 weeks of resistance training when 40 grams of protein is consumed either before sleep or immediately after exercise? Are there differences in cognitive performance during 12 weeks of resistance training when 40 grams of protein is consumed either before sleep or immediately after exercise?
This study is a randomized double-blind placebo-controlled study. Participants will be randomly allocated into 1 of 3 groups. All three groups will perform the same 12-week resistance exercise training program two times per week and consume 40 g of protein: 1) Immediately post-exercise, 2) 30 minutes prior to sleep, or 3) no supplemental protein (control). Test of muscle growth and strength, and cognitive performance will be measure before, during, and after the exercise training program.
Researchers will compare the 3 conditions to determine if consume protein after exercise or before sleep during 12 weeks of resistance exercise training affects muscle growth and strength, and cognitive performance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 75 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Male between 60-75 years old at the time of enrollment.
排除标准
- •Diagnosis of cardiac or peripheral vascular disease
- •Stroke, kidney dysfunction
- •Metabolic disease
- •Uncontrolled hypertension
- •Orthopedic limitations
- •Skeletal muscle complications
- •Milk allergy
- •Psychiatric conditions
- •Use of psychotropic drugs
- •Cognitive impairment (scoring 26 points or less on the Montreal Cognitive Assessment)
- •Participation in a structured regular exercise program within the past 6 months
- •Actively attempting to increase or decrease body mass
- •Body mass index (BMI) of ≥ 35 kg/m2
结局指标
主要结局
Muscle thickness
时间窗: Week 0, 6, and 12
Change in muscle thickness of the quadriceps muscles in centimeters from week 0 (baseline) to week 6 (midpoint) to week 12 (end of study).
次要结局
- Maximum muscular strength(Week 0, 6, and 12)
- Nitrogen balance(Week 0 and 12)
- Cognitive performance(Week 0 and 12)
- Total sleep time(Week 0 and 12)
- Measures associated with sleep(Week 0 and 12)
- Muscle power(Week 0, 6, and 12)
- Measures associated appetite(Week 0, 6, and 12)
- Mood(Week 0 and 12)
- Free insulin-like growth factor 1(Week 0 and 12)
- Sleep latency(Week 0 and 12)
研究者
Alexander Klemp
Principal investigator
Florida State University