Assessment of wound healing in periodontal flaps closed using N-Hexyl cyanoacrylate and Isoamyl 2-cyanoacrylate glue
Phase 2
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2024/02/062586
- Lead Sponsor
- Yogita Uttam Landge
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Chronic periodontitis subjects indicated for periodontal flap surgery.
Exclusion Criteria
1. Subjects with any pre-existing pathology.
2. Subjects with systemic diseases which delays the healing, cardiovascular
diseases, poorly controlled diabetes, HIV, cancer, haemorrhagic disorders.
3. Subjects having history of drug allergy, food allergy or allergy to polymers in
cyanoacrylate, glues, tissue adhesives.
4. Pregnant or lactating women.
5. Subjects using tobacco (In any form).
6. Chronic use of antimicrobial, ant-inflammatory drugs and other medications 6
months prior to the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Wound healing index (Landry, Turnbull, and Howley index) <br/ ><br>2. Pain score (Visual Analogue Scale) <br/ ><br>3. Plaque indexTimepoint: 7th day, 15th day, 1 month follow-up
- Secondary Outcome Measures
Name Time Method Histological examinationTimepoint: 7th day