Should probiotics be used as adjuvants in the treatment of periodontitis?

Not Applicable

• Conditions: Periodontitis; Oral Health

• Registration Number: ISRCTN71877931
• Lead Sponsor: Instituto Superior de Ciências da Saúde Egas Moniz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-11-11
• Last Update Posted: 21 November 2022
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 156

Inclusion Criteria

1. Adults aged 18-65 years old diagnosed with untreated periodontitis
2. Adults aged 18-65 years old without periodontitis (health periodontal)

Exclusion Criteria

1. Unsigned informed consent
2. Pregnant and lactating women
3. Systemic diseases (eg inflammatory bowel diseases, diabetes, infectious diseases, transplant recipients, etc.)
4. Use of certain medications (eg corticoids, cyclosporine, xerostomy medications, NSAIDs, etc.)
5. Taking antibiotics and/or probiotics in the last 3 months
6. Use of antiseptics
7. Drug and/or alcohol abuse, smoking
8. Chemotherapy, radiotherapy for less than 1 year
9. Periodontal treatment for less than 6 months
10. Mental illness
11. Intolerance to lactose, gluten or tablet component
12. Participants with incomplete data or not using ¼ of the pills

Study & Design

• Study Type: Interventional
• Study Design: Not specified