Probiotics in the Treatment of Gum Disease

Not Applicable

Recruiting

• Conditions: Periodontal Diseases; C23.550.291.500

• Registration Number: RBR-6cghbsd
• Lead Sponsor: niversidade Estadual de Ponta Grossa

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-07-25
• Last Update Posted: 22 August 2023
• Study Completion: 2025-01-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

The inclusion criteria for the study will be patients with mild to severe periodontal disease. Over 18 years of age. Under medical follow-up due to chronic diseases. The criteria for classifying the patient's condition as periodontal disease are based on attachment loss, probing depth, and pattern of bone loss. Stage I has interproximal attachment loss of 1-2 mm and probing depths of up to 4 mm. Stage II has interproximal attachment loss of 3-4 mm and probing depths of up to 5 mm. Stage III and IV have interproximal attachment loss of 5 mm or more, with bone loss and tooth loss

Exclusion Criteria

Not eligible for the study: Patients undergoing periodontal or orthodontic maintenance. Pregnant or lactating women. Patients with uncontrolled severe systemic disease. Psychiatric problems. Local pathological alterations. Volunteers requiring tooth extraction. Need for antibiotic prophylaxis. Patients who have used analgesic and anti-inflammatory drugs up to 12 hours before treatment. Alcoholism. Smokers. Dentin hypersensitivity or other pulpal pathologies

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To verify if the local use (intrabuccal) of probiotics associated with non-surgical periodontal treatment contributes to the periodontal clinical parameters in patients with chronic systemic diseases.

Secondary Outcome Measures

Name	Time	Method
To verify whether probiotic therapy in the treatment of periodontal disease contributes to improved quality of life after performing non-surgical periodontal treatment.;To verify whether probiotic therapy in the treatment of periodontal disease contributes to stability of hemodynamic parameters (systemic blood pressure, heart rate, and oxygen saturation) after non-surgical periodontal treatment.;To verify whether probiotic therapy in the treatment of periodontal disease contributes to improvement in masticatory performance after treatment.;Check the presence of residual calculus after non-surgical periodontal treatment.