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Probiotics use for gum disease treatment

Not Applicable
Recruiting
Conditions
Gingivitis
Periodontitis
Probiotics
C07.465.714.533
C07.465.714.258.480
G07.203.300.456.500
Registration Number
RBR-2sdy28
Lead Sponsor
niversidade Veiga de Almeida
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
Not specified
Inclusion Criteria

Volunteers must present Periodontitis; presence of probing pocket depth > 3 mm in association with clinical attachment loss > 3 mm in at least 2 sites of 2 non-adjacent teeth; They must also present more than 20 teeth; age between 30 to 70 years old.

Exclusion Criteria

Cigarete smokers; history of previous periodontal treatment; antibiotics use within the past 6 months; pregnancy; presence of acute or necrotizing lesions; history of diabetes; rheumatic fever; neurological deficiencies; immunological diseases; use of medications that affect periodontal tissues such as phenytoin, cyclosporine, nifedipine and anti-inflammatories.

Study & Design

Study Type
Intervention
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Primary outcome: Statistically significative clinical attachment level average reduction in the pre and post treatment measurements (in milimeters). Verified by clinical probing in 4 sites per tooth using standard periodontal probe; Data collected pre-treatment and 30, 60 and 90 days after the intervention.
Secondary Outcome Measures
NameTimeMethod
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