Probiotics use for gum disease treatment
- Conditions
- GingivitisPeriodontitisProbioticsC07.465.714.533C07.465.714.258.480G07.203.300.456.500
- Registration Number
- RBR-2sdy28
- Lead Sponsor
- niversidade Veiga de Almeida
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Volunteers must present Periodontitis; presence of probing pocket depth > 3 mm in association with clinical attachment loss > 3 mm in at least 2 sites of 2 non-adjacent teeth; They must also present more than 20 teeth; age between 30 to 70 years old.
Cigarete smokers; history of previous periodontal treatment; antibiotics use within the past 6 months; pregnancy; presence of acute or necrotizing lesions; history of diabetes; rheumatic fever; neurological deficiencies; immunological diseases; use of medications that affect periodontal tissues such as phenytoin, cyclosporine, nifedipine and anti-inflammatories.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome: Statistically significative clinical attachment level average reduction in the pre and post treatment measurements (in milimeters). Verified by clinical probing in 4 sites per tooth using standard periodontal probe; Data collected pre-treatment and 30, 60 and 90 days after the intervention.
- Secondary Outcome Measures
Name Time Method