Research between gut microbiome and probiotics in coronary artery disease
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0005393
- Lead Sponsor
- Kyung Hee University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 230
(1) Target patients: Patients who underwent coronary
angiography with chest pain (2) Selection criteria 1) Adults over 19 2) A person
who can understand the purpose and contents of this study and voluntarily
consent after being fully explained. 3) Cardiovascular disease and control group
i. Cardiovascular disease ? Patients who underwent coronary intervention for
more than 70% of stenosis in one or more coronary arteries ? Patients with
myocardial infarction ? Patients with left ventricular dysfunction
(LVEF<45%) ii. Control group: normal coronary artery and normal heart
function
1) Those who do not have voluntary consent, such as
cognitive impairment and vulnerable subjects 2) Women of childbearing age or
pregnant women 3) Patients suspected of active infection 4) Those who are using
systemic antibiotics or receiving immunosuppressive treatment 5) People who have
allergies or side effects to intestinal lactic acid bacteria 6) Hemodynamically
unstable myocardial infarction patient 7) Uncontrolled hypertension (180/110
mmHg), arrhythmia patients 8) Patients with liver failure and kidney
failure
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relative proportion of specific bacteria in extracellular <br>vesicles
- Secondary Outcome Measures
Name Time Method