CTRI/2022/12/048400尚未招募不适用
A split face study to compare the efficacy of platelet rich plasma combined with micro needling versus micro needling alone for treatment of acne scars
Jeyashree1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2023年1月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- To compare the mean reduction in acne scar using Goodman Baron quantitative scale of assessment for acne scars
研究概览
简要总结
- Acne scar is a major cosmetic concern for a patient and presents a challenge to a dermatologists due to lack of effective treatment modalities.[10]
- Although many treatment modalities are currently being used, they have shown improvement to a limited extent with possible side effects. (11)
- Multiple minimally invasive sessions of micro needling is an effective treatment for post acne atrophic scars as it stimulates the repair processes with the advantage of being relatively risk free, in office procedure with minimal patient recovery time (12)
- PRP provides various growth factors which aid in quick wound healing
- This study proposes that PRP can be used as an effective adjuvant therapy to be used along with standard micro needling therapy
- All previously done studies showed no significant change in Goodman and barons score at the end point. This study is to perform the procedure in a Fitzpatrick 4 to 6 skin type with southern type of climatic conditions and to compare the efficacy and adverse effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •grade 2 to grade 4 atrophic acne scars (based on Goodman and Baron’s qualitative classification) ,with quantitatively equal scores on both halves of the face ,without any active acne and who are willing to participate in the study.
排除标准
- •1.Positive history of keloidal tendency.
- •2.Positive history of bleeding or platelet disorder.
- •4.Presence of any acute infection on face like, herpes, folliculitis.
- •5.Patients of HIV, HBsAg, or any chronic illness.
- •6.Pregnancy.
结局指标
主要结局
To compare the mean reduction in acne scar using Goodman Baron quantitative scale of assessment for acne scars
时间窗: 4 months
次要结局
- compare photographs pre and post treatment of both sides of the face using the assessment by an independent physician (dermatologist)
- compare patient satisfaction scores for either side of the face before treatment and 1month after the end of the last session(4 months)
研究者
研究点 (1)
Loading locations...
相似试验
招募中
Unknown
Study of acne scars and research on best treatment modality for depressed acne scarsCTRI/2023/03/050273Yenepoya Medical College Hospital
已完成
不适用
2940nm Er:YAG Laser Versus Benzoyl Peroxide Gel for the Treatment of Inflammatory AcneAcne VulgarisNCT01472900Chulalongkorn University25
招募中
不适用
Study of acne scars and research on best treatment modality for depressed acne scarsCTRI/2023/03/050273Yenepoya Medical College Hospital188
尚未招募
不适用
To compare the efficacy of laser alone versus laser with topical application of insulin in the treatment of acne scars over the faceCTRI/2025/06/088591Dr Sanjay Mailare B60
Unknown
不适用
Comparison of 1550nm Fractional Laser Alone Versus in Combination With Microneedling for the Treatment of Acne ScarsAcne ScarsNCT03901417Massachusetts General Hospital10