Comparing effect of injecting platelet rich plasma with microneedling versus micro needling alone on face for treatment of post acne scars

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/12/048400
• Lead Sponsor: Jeyashree

Brief Summary

- Acne scar is a major cosmetic concern for a patient and presents a challenge to a dermatologists due to lack of effective treatment modalities.[10]

- Although many treatment modalities are currently being used, they have shown improvement to a limited extent with possible side effects. (11)

- Multiple minimally invasive sessions of micro needling is an effective treatment for post acne atrophic scars as it stimulates the repair processes with the advantage of being relatively risk free, in office procedure with minimal patient recovery time (12)

- PRP provides various growth factors which aid in quick wound healing

- This study proposes that PRP can be used as  an effective adjuvant therapy to be used along with standard micro needling therapy

- All previously done studies showed no significant change in Goodman and barons score at the end point. This study is to perform the procedure in a Fitzpatrick 4 to 6 skin type with southern type of climatic conditions and to compare the efficacy and adverse effects.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-06-12
• Study Start: 2023-01-01

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

grade 2 to grade 4 atrophic acne scars (based on Goodman and Baron’s qualitative classification) ,with quantitatively equal scores on both halves of the face ,without any active acne and who are willing to participate in the study.

Exclusion Criteria

• 1.Positive history of keloidal tendency.
• 2.Positive history of bleeding or platelet disorder.
• 4.Presence of any acute infection on face like, herpes, folliculitis.
• 5.Patients of HIV, HBsAg, or any chronic illness.
• 6.Pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the mean reduction in acne scar using Goodman Baron quantitative scale of assessment for acne scars	4 months

Secondary Outcome Measures

Name	Time	Method
compare photographs pre and post treatment of both sides of the face using the assessment by an independent physician (dermatologist)
compare patient satisfaction scores for either side of the face before treatment and 1month after the end of the last session	4 months

Trial Locations

Locations (1)

Indira gandhi medical college and research institute; 🇮🇳 Pondicherry, PONDICHERRY, India

Indira gandhi medical college and research institute

🇮🇳Pondicherry, PONDICHERRY, India

Jeyashree

Principal investigator

8056699678

jeyashreedamodaran@gmail.com