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Therapeutic Omegas for Triglyceride Suppression

Not Applicable
Recruiting
Conditions
Pregnancy
Registration Number
NCT04349475
Lead Sponsor
University of Colorado, Denver
Brief Summary

This study plans to learn more about how an omega-3 fatty acid supplement effects triglyceride levels in pregnancy. Triglycerides are a type of fat found in your blood. Your body converts extra calories into triglycerides to be stored and used later for energy. It is normal for triglyceride levels to go up during pregnancy however some women have levels that are \~30-40% higher than normal when they reach their third trimester of pregnancy. Having high triglycerides in pregnancy may be related to an increased chance of having a baby that is large for their age. The goal of this study is to determine if taking an omega-3 fatty acid supplement can slow the rise in triglyceride levels later in pregnancy.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Pregnant women between the ages of 21-39 yrs
  • Pre-pregnancy BMI 28-39
  • Fasting Triglyceride ≥120 mg/dL measured by 15 wks
Exclusion Criteria
  • Pre-gestational diabetes or prediabetes
  • History of gestational diabetes,
  • History of pre-eclampsia, spontaneous pre-term delivery, or gestational hypertension <34wks
  • Tobacco or illicit substance use
  • Chronic steroid use

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Maternal Fasting and Postprandial Triglycerides34 weeks gestational age

Differences in maternal fasting and postprandial triglycerides between groups

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

University of Colorado/Anschutz Medical Campus

🇺🇸

Aurora, Colorado, United States

University of Oklahoma Health Sciences Center

🇺🇸

Oklahoma City, Oklahoma, United States

University of Colorado/Anschutz Medical Campus
🇺🇸Aurora, Colorado, United States
Emily Dunn, RD
Contact
303-724-0320
Emily.2.Dunn@cuanschutz.edu
Linda A Barbour, MD, MSPH
Sub Investigator
Jacob E Friedman, PhD
Sub Investigator

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