NCT03281473
Unknown
Not Applicable
Comparison of Positive End Expiratory Pressure Titration Methods in Patients With Acute Respiratory Distress Syndrome: a Physiological Study
University Hospital, Angers1 site in 1 country20 target enrollmentOctober 2, 2018
ConditionsAcute Respiratory Distress Syndrome
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Respiratory Distress Syndrome
- Sponsor
- University Hospital, Angers
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Short-term effects of 2 PEEP titration strategies on gas exchange
- Last Updated
- 7 years ago
Overview
Brief Summary
This study aims at assessing the short-term physiological effects of 2 positive end expiratory pressure titration strategies in patients with ARDS.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age\> 18 years
- •Moderate or severe ARDS
- •Consent to participation obtained from a relative
Exclusion Criteria
- •Protect adult
- •Pregnant or breastfeeding woman
- •No-affiliation to the social security scheme
- •Contra-indication to the placement of an esophageal pressure measuring catheter
- •Pneumothorax
- •Hemodynamic and / or respiratory instability
- •Extra-corporeal membrane oxygenation
Outcomes
Primary Outcomes
Short-term effects of 2 PEEP titration strategies on gas exchange
Time Frame: 2 hours 15 minutes
Secondary Outcomes
- Short-term effects of 2 PEEP titration strategies on hemodynamics(2 hours 15 min)
- Short-term effects of 2 PEEP titration strategies on respiratory mechanics(2 hours 15 min)
Study Sites (1)
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