A Prospective Randomised study to compare the efficacy of volume controlled ventilation and pressure support ventilation in patients undergoing coronary artery bypass grafting off pump surgeries.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Development of post-operative pulmonary complications:
研究概览
简要总结
This comparative study aimed to evaluate the efficacy of volume controlled ventilation versus pressure controlled ventilation modes during surgery in preventing postoperative pulmonary complications in patients undergoing coronary artery bypass grafting. patients scheduled for elective CABG were randomly assigned to receive either VCV or PVC intraoperatively. The objective of the study was to assess the incidence of post operative pulmonary complications such as atelectasis, pneumonia, hypoxaemia and prolonged ventilation in postoperative period. The study aimed to identify the ventilation strategy that offers superior pulmonary protection and better postoperative respiratory outcomes. in patients undergoing CABG.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)(—)
- 性别
- All
入选标准
- •18 years of age or older
- •Scheduled for elective cardiac surgery with general anesthesia, invasive mechanical ventilation, complete median sternotomy.
排除标准
- •Patients were excluded in case of emergent or redo surgeries
- •Patients with history of COPD.
- •Patients with known pulmonary Hypertension
- •Patients with EF less than 40% in Echocardiography
- •Patients with significant history of smoking addiction
- •Body mass index more than 35 kg/ m2
- •Obstructive sleep apnea
- •Patient Refusal.
结局指标
主要结局
Development of post-operative pulmonary complications:
时间窗: 30minutes/60minutes/2hours/4hours/8hour/16hours/24hours/48hours/72hours
(Post-extubation respiratory failure, Bronchospasm, Severe trachea–bronchial congestion,
时间窗: 30minutes/60minutes/2hours/4hours/8hour/16hours/24hours/48hours/72hours
Respiratory acidosis, Suspected or confirmed pneumonia, Pleural effusion, Radiological
时间窗: 30minutes/60minutes/2hours/4hours/8hour/16hours/24hours/48hours/72hours
atelectasis, acute respiratory distress syndrome, prolonged invasive ventilation associated
时间窗: 30minutes/60minutes/2hours/4hours/8hour/16hours/24hours/48hours/72hours
with hypoxemia)
时间窗: 30minutes/60minutes/2hours/4hours/8hour/16hours/24hours/48hours/72hours
次要结局
- Duration of ICU stay(At baseline)
研究者
Dr Kiran Muthu Rajah
Sri Ramachandra Institute of Higher Education and Research
