NCT05268692招募中2 期
Neoadjuvant Chemotherapy for Pancreatic Cancer; GS vs. GnP
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- overall survival
研究概览
简要总结
The effect of neoadjuvant chemotherapy for pancreatic cancer was gradually established. However it has been not clarified which regimen of neoadjuvant treatment for pancreatic cancer is the best.
详细描述
gemcitabine plus S-1 versus gemcitabine plus nab-paclitaxel
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •elective pancreatectomy for pancreatic cancer
排除标准
- •a previous cancer surgery a body weight loss of >10% during the 6 months before surgery the presence of distant metastases seriously impaired function of vital organs because of respiratory, renal, or heart disease.
研究组 & 干预措施
GS
Active Comparator
gemcitabine plus S-1
干预措施: GS (Drug)
GnP
Active Comparator
gemcitabine plus nab-paclitaxel
干预措施: GnP (Drug)
结局指标
主要结局
overall survival
时间窗: 5 years
postoperative survival
次要结局
- adverse events(up to 24 weeks)
研究者
Takehiro Okabayashi
Department of Surgery
Kochi University
研究点 (1)
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