NCT00813553CompletedNot Applicable
Effect of Two 8-week β-alanine Supplementation Protocols on Muscle Carnosine
Société des Produits Nestlé (SPN)2 sites in 1 country30 target enrollmentStarted: December 1, 2008Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 30
- Locations
- 2
- Primary Endpoint
- muscle carnosine concentration
Study Overview
Brief Summary
Carnosine is a natural acid buffering substance of muscle. The primary objective of this study is to test whether a nutritional supplement of beta-alanine enhances carnosine content in muscle.
Detailed Description
Volunteers will be randomized to receiving 3 nutritional supplements. Two supplements contain beta-alanine at different doses, the third supplement is a placebo.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Stable health as evaluated by medical evaluation
- •Body mass index higher than 18 kg/m2
- •Body mass index lower than 25 kg/m2, unless body fat is less than 20%
Exclusion Criteria
- •intolerance to β-alanine,
- •allergy to soy, fish and crustacean
- •participation in another intervention study
- •consumer of dietary supplement susceptible to contain beta-alanine
- •determined to have very high baseline muscle carnosine concentration
Outcomes
Primary Outcomes
muscle carnosine concentration
Time Frame: 0 to 8 weeks
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (2)
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