The Effect of 28 Days of Beta-alanine Supplementation on the Physical Working Capacity at Heart Rate Threshold (PWCHRT)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 35
- Locations
- 2
- Primary Endpoint
- Physical working capacity at heart rate threshold
Study Overview
Brief Summary
Beta-alanine, as a method to increase muscle carnosine, has been shown to enhance muscle buffering capacity and delay fatigue. Various fatigue tests have been utilized to examine the effectiveness of beta-alanine supplementation. The physical working capacity test has been used to show significant increases in physical working capacities following supplementation. The physical working capacity tests were originally developed by Moritani et al. 1981 and Devries et al. 1982 to measure the point of onset of muscular fatigue. It is hypothesized that beta-alanine will increase physical working capacity at heart rate threshold, thereby signifying a delay in fatigue.
Detailed Description
An equal number of men and women will be recruited [Men, n=20 (10 placebo [PL]; 10 beta-alanine (Active)]; [Women,n=20 (10 PL; 10 Active)]. Men and women will be randomly assigned to respective groups to allow for equal numbers in supplement and placebo groups.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Factorial
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 18 Years to 35 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Between the ages of 18-35 years old
- •Be recreationally active (defined as accumulating 1-5 hours of moderate intensity
- •Exclusion Criteria
- •Any health risks or indicators that would prevent them from participating in physical activity, as determined by a health history questionnaire
- •Must not have taken performance enhancing supplements containing beta-alanine or creatine during the last 3 months
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Physical working capacity at heart rate threshold
Time Frame: 0 to 4 weeks
Secondary Outcomes
No secondary outcomes reported
Investigators
Abbie Smith-Ryan, PhD
Assistant Professor
University of North Carolina, Chapel Hill