Effect of Beta-Alanine on Heart Rate Response

Not Applicable

Completed

• Conditions: Exercise; Fatigue
• Interventions: Dietary Supplement: Beta-alanine; Dietary Supplement: Placebo

• Registration Number: NCT01745016
• Lead Sponsor: University of North Carolina, Chapel Hill

Brief Summary

Beta-alanine, as a method to increase muscle carnosine, has been shown to enhance muscle buffering capacity and delay fatigue. Various fatigue tests have been utilized to examine the effectiveness of beta-alanine supplementation. The physical working capacity test has been used to show significant increases in physical working capacities following supplementation. The physical working capacity tests were originally developed by Moritani et al. 1981 and Devries et al. 1982 to measure the point of onset of muscular fatigue. It is hypothesized that beta-alanine will increase physical working capacity at heart rate threshold, thereby signifying a delay in fatigue.

Detailed Description

An equal number of men and women will be recruited \[Men, n=20 (10 placebo \[PL\]; 10 beta-alanine (Active)\]; \[Women,n=20 (10 PL; 10 Active)\]. Men and women will be randomly assigned to respective groups to allow for equal numbers in supplement and placebo groups.

Study Timeline

• Study First Submitted: 2012-12-05
• Study First Submitted QC: 2012-12-05
• Study First Posted: 2012-12-07
• Study Start: 2013-01
• Status Verified: 2013-04
• Primary Completion: 2013-04
• Study Completion: 2013-04
• Last Update Submitted: 2013-04-29
• Last Update Posted: 2013-04-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• Between the ages of 18-35 years old
• Be recreationally active (defined as accumulating 1-5 hours of moderate intensity

Exclusion Criteria

• Any health risks or indicators that would prevent them from participating in physical activity, as determined by a health history questionnaire
• Must not have taken performance enhancing supplements containing beta-alanine or creatine during the last 3 months

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Beta-Alanine	Beta-alanine	beta-alanine
Placebo	Placebo	placebo

Primary Outcome Measures

Name	Time	Method
Physical working capacity at heart rate threshold	0 to 4 weeks

Trial Locations

Locations (1)

UNC Exercise and Sport Science; 🇺🇸 Chapel Hill, North Carolina, United States