NCT03655041已完成不适用
24-Weeks of β-Alanine Ingestion on Muscle Taurine and Clinical Blood Parameters in Healthy Males
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 主要终点
- Muscle taurine content in mmol/kg
研究概览
简要总结
Although β-alanine (BA) has been shown to be an effective ergogenic aid, little information exists on the safety of chronic supplementation despite potential concerns. The aim of this study was to investigate the effects of chronic BA supplementation on muscle taurine content, blood clinical markers and sensory side-effects during 24 weeks of BA supplementation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy males
排除标准
- •Chronic disease
- •Prior or current use of steroids
- •Use of creatine in the last 6 months
- •Use of beta-alanine in the last 6 months
研究组 & 干预措施
Beta-Alanine
Experimental
6.4 g/day of beta-alanine for 24 weeks
干预措施: Beta-alanine (Dietary Supplement)
Placebo
Placebo Comparator
6.4 g/day of maltodextrin for 24 weeks
干预措施: Placebo (Dietary Supplement)
结局指标
主要结局
Muscle taurine content in mmol/kg
时间窗: Up to 24 weeks
Change in the content of taurine in muscle will be determined using High-Pressure Liquid Chromatography of muscle biopsies
次要结局
- Albumin; globulin; creatinine in mg/dL(Up to 24 weeks)
- Aspartate transaminase; alanine aminotransferase; alkaline phosphatase; lactate dehydrogenase and creatine kinase in U/L(Up to 24 weeks)
研究者
Bruno Gualano
Principal Investigator
University of Sao Paulo
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