Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Psychological Stress
- Sponsor
- Baylor University
- Enrollment
- 170
- Locations
- 1
- Primary Endpoint
- Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline)
- Status
- Completed
- Last Updated
- 10 months ago
Overview
Brief Summary
The present study will examine cardiovascular, metabolic, and neural responses to acute psychological stress using a cross-sectional approach.
Detailed Description
All participants in this study will undergo an acute psychological stress paradigm, consisting of two acute psychological stress tasks (MSIT and Stoop). There is no formal randomization since al participants are randomized to undergo the acute psychological stress tasks.
Investigators
Annie Ginty
Assistant Professor
Baylor University
Eligibility Criteria
Inclusion Criteria
- •18-30 years old
Exclusion Criteria
- •Chronic medical or neurological condition
- •Current illness or infection
- •Any condition that would prohibit engaging in physical exercise
- •Any metal implants in body
- •Claustrophobia
Outcomes
Primary Outcomes
Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline)
Time Frame: 18 minutes (approximately 9 minutes for each task)
Stressor-evoked oxygen consumption. (Oxygen consumption during acute psychological stress task - Oxygen consumption during resting baseline).
Heart Rate (Bpm) Measured by Electrocardiogram
Time Frame: 18 minutes (approximately 9 minutes for each stress task)
Stressor-evoked heart rate. (Heart rate during acute psychological stress task - Heart rate during resting baseline).
Neural Activity Measured by fMRI
Time Frame: 18 minutes (approximately 9 minutes for each stress task).
Stressor-evoked neural activity. Incongruent-vs-Congruent t at the group-level, filtered at 0.05 after FDR correction and with a cluster extent of 50 voxels.