Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 170
- 试验地点
- 2
- 主要终点
- Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline)
研究概览
简要总结
The present study will examine cardiovascular, metabolic, and neural responses to acute psychological stress using a cross-sectional approach.
详细描述
All participants in this study will undergo an acute psychological stress paradigm, consisting of two acute psychological stress tasks (MSIT and Stoop). There is no formal randomization since al participants are randomized to undergo the acute psychological stress tasks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-30 years old
排除标准
- •Chronic medical or neurological condition
- •Current illness or infection
- •Any condition that would prohibit engaging in physical exercise
- •Any metal implants in body
- •Claustrophobia
结局指标
主要结局
Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline)
时间窗: 18 minutes (approximately 9 minutes for each task)
Stressor-evoked oxygen consumption. (Oxygen consumption during acute psychological stress task - Oxygen consumption during resting baseline).
Heart Rate (Bpm) Measured by Electrocardiogram
时间窗: 18 minutes (approximately 9 minutes for each stress task)
Stressor-evoked heart rate. (Heart rate during acute psychological stress task - Heart rate during resting baseline).
Neural Activity Measured by fMRI
时间窗: 18 minutes (approximately 9 minutes for each stress task).
Stressor-evoked neural activity. Incongruent-vs-Congruent t at the group-level, filtered at 0.05 after FDR correction and with a cluster extent of 50 voxels.
次要结局
未报告次要终点
研究者
Annie Ginty
Assistant Professor
Baylor University