Respiratory muscle training to improve exercise capacity and quality of life in people with pulmonary arterial hypertensio

• Conditions: Pulmonary Hypertension; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system

• Registration Number: ACTRN12616000429459
• Lead Sponsor: niversity of Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-04-04
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Inclusion criteria are age greater than or equal to 18 years with either idiopathic or connective tissue disease related pulmonary arterial hypertension (mean arterial pressure of age greater than 25mmHg at rest assessed by right heart catherization) with NYHA Class II/III.

Exclusion Criteria

Exclusion criteria are major intellectual instability, non-English speaking background, clinically unstable patients, lung volumes < 80% predicted, pregnancy and change in medication within 3 months of study commencement.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Peak oxygen uptake measured at cardiopulmonary exercise testing using a ramp protocol and open circuit spirometer.[10 weeks]

Secondary Outcome Measures

Name	Time	Method
6 minute walk distance.[10 weeks];Quality of life (Sf-36)[10 weeks]