Effects of Breaks of Sedentary Behavior With Isometric Exercise in Cardiovascular Health Indicators of Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 17
- 试验地点
- 2
- 主要终点
- Change from baseline in vascular function at 12 weeks
研究概览
简要总结
The goal of this study is to analyze the chronic effects of sedentary behavior breaks using the leg extension isometric exercise in the cardiovascular health indicators of healthy adults exposed to prolonged time in the sitting position. The patients recruited will be randomized into two groups: leg extension isometric training (TIE) and control group (CG). The TIE group will perform 12 weeks of isometric training. The CG will be advised not to change their routine activities, especially diet and physical activities.In the pre and post-intervention periods cardiovascular measures will be obtained.
详细描述
Long periods in sedentary behavior promote deterioration of vascular function, which is directly associated with the occurence of chronic noncommunicable diseases. In this context, the execution of interruptions in this behavior (breaks) is recommended. Studies have shown benefits of isometric training in vascular function, which could be useful to minimize the consequences of time spent in sedentary behavior. Thus, the goal of this study is to analyze the chronic effects of sedentary behavior breaks using leg extension isometric exercise in the cardiovascular health indicators of adults exposed to prolonged time in the sitting position. The target population of the study will consist of healthy subjects above 18 years of age of both genders. All subjects will be submitted to measurements of endothelial function, blood pressure and cardiac autonomic modulation. After these measurements, the subjects will be randomized into two groups: leg extension isometric training group (TIE) and control group (CG). After 12 weeks both groups will be submitted to the same measurements from pre-intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •No diagnostic of cardiovascular diseases or diabetes
- •Do not present high cardiovascular risk
- •Do not participate in an exercise program in the previous six months
- •Occupational activity that requires more than six hours of sitting time per day
- •Do not be a smoker or make use of medications
排除标准
- •Adherence to the training sessions inferior to 85%
- •Adherence to another supervised exercise program
- •Change the characteristics of the occupational activities
结局指标
主要结局
Change from baseline in vascular function at 12 weeks
时间窗: Baseline and 12 weeks
Vascular function will be measured before and after 12 weeks of intervention on the intervention and control groups by a bidimensional ultrasonography device with spectral Doppler and linear transducer.
次要结局
- Changes from baseline in blood pressure at 12 weeks(Baseline and 12 weeks)
- Change from baseline in cardiac autonomic modulation at 12 weeks(Baseline and 12 weeks)
研究者
Raphael Mendes Ritti Dias
Professor
University of Nove de Julho