Acute Effects of Breaks From Sedentary Behavior With Dual Tasks on Cerebral Blood Flow, Cognitive Function, Blood Pressure and Vascular Function in the Elderly
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aging
- Sponsor
- University of Nove de Julho
- Enrollment
- 27
- Locations
- 1
- Primary Endpoint
- Cognitive function - verbal fluency [number of animal names reported]
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The aim of this project will be to compare the acute effects of breaks from sedentary behavior using dual-tasking on cerebral blood flow, vascular function, cognitive functions and blood pressure in elderly people. Participants will perform, in random order, three experimental sessions (control, break with dual-task and standard break ([walk]). All sessions will have a period of 4 hours in sedentary behavior. In the standard break session and in the break session with dual-task participants will take walking and dual-task breaks every 30 minutes, and in the control session they will remain seated without breaks. Before and after this period, cerebral blood flow, vascular function, cognitive functions and blood pressure will be assessed.
Investigators
Raphael Mendes Ritti Dias
Principal Investigator
University of Nove de Julho
Eligibility Criteria
Inclusion Criteria
- •aged 60 years or over
- •be physically independent based on the Katz Test
- •have no history of heart attack
- •not having suffered a stroke
- •not have heart failure
- •do not have joint problems that prevent them from carrying out experimental sessions
- •do not have a history of neurodegenerative diseases
- •obtain ≥ 26 points in the Montreal Cognitive Assessment (MoCA)
- •are not involved in the practice of regular, systematic physical activity more than once a week over the last six months prior to the start of the study
- •not be smokers and morbidly obese.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Cognitive function - verbal fluency [number of animal names reported]
Time Frame: Before and 35 minutes after the intervention
The task will consist of recalling words that begin with the letter "F", for 60 seconds. The final score will be determined according to the number of correct words reported in 60 seconds. In the semantic modality, participants must evoke as many animals as possible in 60 seconds. The final score will be determined according to the number of animal names reported in 60 seconds.
Cerebral blood velocity [centimeters per second]
Time Frame: Before and 20 minutes after the intervention for 5 minutes
Mean arterial velocity of middle cerebral artery will be measured using a transcranial doppler
Cognitive function - The Trail Making Tests [seconds]
Time Frame: Before and 30 minutes after the intervention
The Trail Making Tests (A and B) will be used to assess executive function and attention. Part A will determine psychomotor speed and require the participant to draw lines connecting sequentially circled numbers, such as drawing a line from 1 to 2, 2 to 3, and 3 to 4. Part B will consist of circled numbers and letters. Participants will be instructed to draw a line as quickly and as accurately as possible from 1 to A, A to 2, 2 to B, B to 3, and so on, until they complete the task. The time in seconds will be recorded in seconds after the end of each stage. After carrying out the tests, the differences between the completion times for part B - A will be calculated.
Cognitive function - Stroop test [seconds]
Time Frame: Before and 32 minutes after the intervention
A computerized version of the Stroop test will be used in this study, using the Testinpacs® program. The tasks will be viewed on a notebook screen approximately 90 cm away from the participant. Answers to a set of tasks will be given as quickly as possible via two buttons. The cognitive portion of the Stroop test will be used as a psychometric test to assess cognition, being related to the executive functions of decision-making and inhibitory control exercised by the prefrontal cortex. The capacity for selective attention and response control will be estimated as the time difference between the third condition and the second condition. Smaller differences will indicate better selective attention and conflict resolution.
Secondary Outcomes
- Resting heart rate [bpm](Before and 10 minutes after the intervention)
- Ambulatory systolic, diastolic, and mean blood pressures monitoring [mmHg](45 minutes after the intervention)
- Resting systolic and diastolic blood pressures [mmHg](Before and 10 minutes after the intervention)
- Vascular function [%](Before and 10 minutes after the intervention)