Comparison of the effect of Methadone and Morphine on postoperative pain following surgery in opium addicted patients
Phase 2
- Conditions
- Opium Addiction.Mental and behavioural disorders due to use of opioids
- Registration Number
- IRCT2013010912074N1
- Lead Sponsor
- Vice chancellor for research, Kerman University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Inclusion criteria are: American Association of Anesthesiologists’ (ASA) classification of I or II; age 20 -65; having thoracic surgery (thoracotomy or incision’s extent of 10cm, without removal of rib and duration of 3 hours or less); more than 12 months history of opium addiction (inhalation form) as described by DSM-IV codes and after obtaining informed consent.
Exclusion criteria are: ASA classification of 3-6 (severe systemic disorders such as Chronic Renal Failure and Chronic Heart Failure); non addicted patients; less than 12 months duration of addiction; addiction to drugs other than opium; consuming less than or more than 390mg of opium per day.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of pain. Timepoint: at first, third, 6th, 12th and 24th hour of post operation time. Method of measurement: Visual Analogue Scale (VAS).
- Secondary Outcome Measures
Name Time Method