Weight Loss and Exercise in Physically Limited Obese Elderly Subjects
- Registration Number
- NCT00146133
- Lead Sponsor
- Washington University School of Medicine
- Brief Summary
The overall purpose of this research is to determine the effect of weight loss and physical training on quality of life, physical function, metabolism, bone strength, body fat and muscle mass.
- Detailed Description
Obesity causes serious medical complications and impairs quality of life. Moreover, in elderly persons, obesity can lead to frailty because of decreased strength, joint function, balance and mobility associated with aging. The primary objective of this study is to evaluate the effect of weight loss and physical training on physical function, body composition...
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 28
Inclusion Criteria
- Obese (BMI 30 or greater) elderly (age 65 years or older) Frailty
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Exclusion Criteria
- Major chronic disease or any condition that would interfere with exercise or dietary restriction, in which exercise or dietary restriction are contraindicated, or that would interfere with interpretation of results. Examples include cardiopulmonary disease, unstable disease, severe orthopedic or neuromuscular impairments, dementia, history of malignancy during the past 5 yr, current use of bone acting drugs.
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method physical function and body composition
- Secondary Outcome Measures
Name Time Method quality of life, metabolic markers
Trial Locations
- Locations (1)
Washington University School of Medicine
🇺🇸St Louis, Missouri, United States