The effect of standard versus energy dense feeds on gastric emptying and glucose metabolism in critically ill patients

Phase 4

Completed

• Conditions: Critical Illness; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12617000384358
• Lead Sponsor: Intensive Care Research Unit, Royal Adelaide Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-15
• Study Completion: 2019-02-28
• Last Update Posted: 5 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

Mechanically ventilated critically ill patients who are:
-Aged >18 years of age
-Receiving or suitable to receive enteral nutrition
-Anticipated to remain mechanically ventilated for a further 48 hours

Exclusion Criteria

Patients will be excluded if they meet one of the following:
-Pregnancy
-Receiving gastrokinetic drugs (including Erythromycin, Metoclopramide, Azithromycin, Domperidone, Prucalopride)
-Gastrointestinal surgery on this admission
-Previous upper gastrointestinal surgery (oesophageal, stomach or duodenal)
-Unable to obtain informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare rate of gastric emptying of a 1 and 2 kcal/ml isocaloric liquid nutrient in critically ill patients using scintigraphy.[ The content of the total stomach at 5, 15, 30, 45, 60, 90, 120 (main), 150, 180, 210 and 240 minutes after the meal will be assessed to determine gastric emptying]