Improving the diagnostic strategy of patients with recurrent differentiated thyroid cancer with PET/CT.
Suspended
- Conditions
- Differentiated thyroid cancerI-124 PET/CTFDG PET/CT
- Registration Number
- NL-OMON27626
- Lead Sponsor
- The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
1. Patients with a history of differentiated thyroid cancer;
2. After complete thyroidectomy and ablation of functional remnants with 131I;
Exclusion Criteria
1. Age < 18 years;
2. Pregnancy;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of futile high-dose 131I treatments that could have been avoided by implementation of pre-therapy imaging based on result of post-therapy scintigraphy.
- Secondary Outcome Measures
Name Time Method 1. Synchronised QA/QC of 124I-PET in the Netherlands;<br /><br>2. Correlations of 124I-PET and FDG-PET with histopathological parameters and Tg;<br /><br>3. Correlation between 124I-PET findings during rhTSH and withdrawal combined with LID.