The Impact of Bariatric Surgery on Estimated Bone Mineral Density in Chinese Obesity Patients: a Retrospective Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Bone Mineral
- Sponsor
- First Affiliated Hospital of Jinan University
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- Postoperative of bone density at 3 months
- Last Updated
- 7 years ago
Overview
Brief Summary
Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including type 2 diabetes. Laparoscopic gastric bypass surgery and laparoscopic sleeve gastrectomy are commonly used in bariatric surgery. Laparoscopic sleeve gastrectomy due to simple operation, good weight loss, and metabolic disease control effect, which is more widely used. However, there are several studies that show an increased chance of gastroesophageal reflux disease after laparoscopic sleeve gastrectomy. Long-term gastroesophageal reflux may lead to Barrett's esophagus or esophageal cancer. Nowadays, the cause of gastroesophageal reflux disease after sleeve gastrectomy is not clear and precautionary measures are not precise.
In this study, prospective randomized controlled trials were conducted to explore the possible causes of bone mineral after bariatric surgery and to explore ways to prevent bone mineral after bariatric surgery.
Investigators
Jingge Yang
Director of bariatric surgery
First Affiliated Hospital of Jinan University
Eligibility Criteria
Inclusion Criteria
- •For the choice of surgical approach, numerous studies have shown that BMI ≧ 45, the general choice of gastric bypass surgery, BMI \<45, you can choose sleeve gastrectomy. The remission rate for T2DM, sleeve gastrectomy has a good result for young patients with shorter duration. In our country, the BMI less than 45 is majorities.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Postoperative of bone density at 3 months
Time Frame: 3 months
bone density in g/cm3
Postoperative of bone density at 6 months
Time Frame: 6 months
bone density in g/cm3
Preoperative of bone density
Time Frame: Preoperative
bone density in g/cm3
Postoperative of bone density at 1 year
Time Frame: 1 year
bone density in g/cm3