the Related Factors of Bariatric Surgery on Bone Mineral Density

Not Applicable

• Conditions: Bone Mineral; Bariatric Surgery
• Interventions: Procedure: sleeve gastrectomy; Procedure: gastric bypass

• Registration Number: NCT03689816
• Lead Sponsor: First Affiliated Hospital of Jinan University

Brief Summary

Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including type 2 diabetes. Laparoscopic gastric bypass surgery and laparoscopic sleeve gastrectomy are commonly used in bariatric surgery. Laparoscopic sleeve gastrectomy due to simple operation, good weight loss, and metabolic disease control effect, which is more widely used. However, there are several studies that show an increased chance of gastroesophageal reflux disease after laparoscopic sleeve gastrectomy. Long-term gastroesophageal reflux may lead to Barrett's esophagus or esophageal cancer. Nowadays, the cause of gastroesophageal reflux disease after sleeve gastrectomy is not clear and precautionary measures are not precise.

In this study, prospective randomized controlled trials were conducted to explore the possible causes of bone mineral after bariatric surgery and to explore ways to prevent bone mineral after bariatric surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-04-01
• Study First Submitted: 2018-06-03
• Status Verified: 2018-09
• Study First Submitted QC: 2018-09-26
• Last Update Submitted: 2018-09-26
• Study First Posted: 2018-09-28
• Last Update Posted: 2018-09-28
• Primary Completion: 2018-12
• Study Completion: 2019-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

-For the choice of surgical approach, numerous studies have shown that BMI ≧ 45, the general choice of gastric bypass surgery, BMI <45, you can choose sleeve gastrectomy. The remission rate for T2DM, sleeve gastrectomy has a good result for young patients with shorter duration. In our country, the BMI less than 45 is majorities.

Exclusion Criteria

-BMI<27.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
bone density	sleeve gastrectomy	bone density
bone density	gastric bypass	bone density

Primary Outcome Measures

Name	Time	Method
Postoperative of bone density at 3 months	3 months	bone density in g/cm3
Postoperative of bone density at 6 months	6 months	bone density in g/cm3
Preoperative of bone density	Preoperative	bone density in g/cm3
Postoperative of bone density at 1 year	1 year	bone density in g/cm3

Trial Locations

Locations (1)

The frist affiliated hospital of Jinan University; 🇨🇳 Guangzhou, Guangdong, China