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Clinical Trials/NCT03689803
NCT03689803
Unknown
Not Applicable

The Impact of Bariatric Surgery on Estimated Lipidemia in Chinese Obesity Patients: a Retrospective Cohort Study

First Affiliated Hospital of Jinan University1 site in 1 country1,000 target enrollmentApril 1, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bariatric Surgery
Sponsor
First Affiliated Hospital of Jinan University
Enrollment
1000
Locations
1
Primary Endpoint
preoperative of choleaterol
Last Updated
7 years ago

Overview

Brief Summary

Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including type 2 diabetes. Laparoscopic gastric bypass surgery and laparoscopic sleeve gastrectomy are commonly used in bariatric surgery. Laparoscopic sleeve gastrectomy due to simple operation, good weight loss, and metabolic disease control effect, which is more widely used. However, there are several studies that show an increased chance of gastroesophageal reflux disease after laparoscopic sleeve gastrectomy. Long-term gastroesophageal reflux may lead to Barrett's esophagus or esophageal cancer. Nowadays, the cause of gastroesophageal reflux disease after sleeve gastrectomy is not clear and precautionary measures are not precise.

In this study, prospective randomized controlled trials were conducted to explore the possible change of lipidemia after bariatric surgery and to explore ways to prevent bariatric surgery after bariatric surgery.

Registry
clinicaltrials.gov
Start Date
April 1, 2018
End Date
December 2019
Last Updated
7 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
First Affiliated Hospital of Jinan University
Responsible Party
Principal Investigator
Principal Investigator

Jingge Yang

Director of bariatric surgery

First Affiliated Hospital of Jinan University

Eligibility Criteria

Inclusion Criteria

  • For the choice of surgical approach, numerous studies have shown that BMI ≧ 45, the general choice of gastric bypass surgery, BMI \<45, you can choose sleeve gastrectomy. The remission rate for T2DM, sleeve gastrectomy has a good result for young patients with shorter duration. In the investigator's country, the BMI less than 45 is majorities.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

preoperative of choleaterol

Time Frame: Preoperate

choleaterol in ml/dl

Postoperative of choleaterol at 3 months

Time Frame: 3 months

choleaterol in ml/dl

Postoperative of choleaterol at 6 months

Time Frame: 6 months

choleaterol in ml/dl

Postoperative of choleaterol at 1 year

Time Frame: 1 year

choleaterol in ml/dl

Secondary Outcomes

  • Preoperative of triglyceride(Preoperative)
  • Postoperative of triglyceride at 3 months(3 months)
  • Postoperative of triglyceride at 6 months(6 months)
  • Postoperative of triglyceride at 1 year(1 year)

Study Sites (1)

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