Exploring the absorption of Anthocyanins from high pigment potatoes

Completed

Conditions: opname carotenoïden
nvt

Registration Number: NL-OMON48594

Lead Sponsor: Wageningen Universiteit

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 10

Inclusion Criteria

* Male
* Age: 18-65 years
* Body Mass Index (BMI) 18-30 kg/m2.

Exclusion Criteria

* Recent history of acute gastro-intestinal conditions (indigestion, diarrhoea, constipation) (over last 2 weeks before screening).
* History of gastro-intestinal (atrophic gastritis, gastric and peptic ulcers, small bowel disease or resection, enterocolitis, Crohn*s disease, bleeding disorders) and/or renal diseases (according to research subjects own statement)
* Use of supplements containing anthocyanins in the last 3 months
* Use of (prescribed) medication during the whole study (excluding paracetamol)
* Smoking
* Current participation in other studies
* Having a medically prescribed diet
* Working or doing an internship or thesis at the Division of Human Nutrition
* Allergic or hypersensitivity for potato

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To explore the absorption of anthocyanins, changes are measured in blood plasma<br /><br>and urine (intact molecules and metabolite excretion products) after<br /><br>consumption of the different test meals. Intact molecules and main metabolites<br /><br>(protocatechuic acid derived, vanillic acid, vanillic acid sulfate, hippuric<br /><br>acid and ferulic acid) will be measured, and metabolic profiling will be used<br /><br>to determine other yet unknown metabolites.<br /><br><br /><br>These study parameters will be monitored from t=0 to t=9 hrs after consumption<br /><br>of the test meal.</p><br>

Secondary Outcome Measures