NCT00936039已完成不适用
The Effect of Immobilization on Myocellular Characteristics in Healthy, Young Males
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- muscle mass, muscle fiber size
研究概览
简要总结
In the present study, the effects of 3 weeks of unloading on muscle mass and muscle fiber characteristics will be determined. In addition, the effects of 6 weeks of recovery will be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •BMI < 30 kg/m2
排除标准
- •Use of medication that may affect haemostasis
- •Subjects with (recent) musculoskeletal/orthopaedic disorders known to affect the outcome of the study or that compromise their ability to walk with crutches
- •Subjects with metal implants in their lower limbs
- •Subjects with known cardiovascular and/or haemostasis disorders
- •Subjects with known severe hypertension
结局指标
主要结局
muscle mass, muscle fiber size
时间窗: 1 week before unloading; immediately (1 day) after unloading and 6 weeks after unloading
次要结局
- muscle strength(1 week before unloading; immediately (1 day) after unloading and 6 weeks after unloading)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
The effect of immobilization on myocellular characteristics in healthy, young malesSarcopenia10028302NL-OMON36909niversiteit Maastricht15
已完成
不适用
The Effect of Aging and Immobilisation on MuscleHealthyNCT00559806Bispebjerg Hospital20
已完成
不适用
The Impact of Leg Immobilization on Postabsorptive and Postprandial Muscle Protein Breakdown in Healthy Young MalesHealthyNCT03934632University of Exeter24
终止
不适用
Sarcopenia in the Acute StrokeStroke, AcuteNCT06603701Centre Hospitalier Régional d'Orléans6
已完成
不适用
Brain and Muscle Plasticity During ImmobilizationMuscle AtrophyNCT05115643McGill University12