The Learning and Memory of the Experience of Pain

Massachusetts General Hospital1 个研究点分布在 1 个国家目标入组 60 人开始时间: 2013年1月1日最近更新: 2019年8月13日

适应症

试验速览

This study investigates the learning and memory of pain.

•Male and female healthy volunteers.
•18-65 years of age.
•Right-handed.
•Fluency in English. Ability to read and understand English; English can be a second language provided that the participant feels that he/she is able to understand all the questions used in the assessment measures.

•Any previous experience with conditioned analgesia/hyperalgesia paradigms.
•Presence of any illness or medication use that is judged to interfere with the trial. For example: psychiatric disorder according to the DSM-IV manual, medication that can influence cognition or emotional processing, i.e. sleep medication, antidepressants, anti-convulsants or opioids.
•Unwillingness to receive brief pain stimulation administered by a heat probe on the hand.
•Instability of responses to experimental heat pain
•Any contraindications to fMRI scanning for subjects in Experiment 2 (including metal implants, claustrophobia, history of head trauma, and pregnancy).
•Peripheral neuropathy.

发起方

申办方类型

Other

责任方

Principal Investigator

主要研究者

Jian Kong

MS, MD

Massachusetts General Hospital

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