Secondary Protective effect of ca-antagonist for ischemic heart attack randominzed parallel comparison with beta-blocker trial
- Conditions
- Ischemic heart disease (post-myocardila infarction angina, angina pectoris)
- Registration Number
- JPRN-UMIN000000930
- Lead Sponsor
- ippon Medical School
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 800
Not provided
1) previous history of hypersensitivity or intolerance of atenolol or benidipine 2) cardiogenic shock 3)diabetic ketoacidosis, metabolic acidosis 4)severe or symptomatic bradycardia, atrioventricular block (II, III degree), sinoatrial block, sick sinus syndrome 5)critical arrhythmia 6)right ventricular failure with pulmonary hypertension 7)congestive heart failure 8)hypotension 9)severe peripheral arterial disease (gangrene etc) 10)untreated pheochromocytoma 11)any women who is pregnant or breastfeeding, or expecting to conceive within the projected duration of the study 12)severe hepatic failure (total bilirubin >2.0mg/dL) 13)severe renal failure (serum creatinin >3.0mg/dL) 14)infection, paralytic or obstractive ileus 15)ongoing or planning treatment with anti-cancer drugs 16)other serious illness or significant abnormalities that the investigator judges inappropriate for the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method cardiovascular evetns including myocardial infarction, angina, silent myocardial ischemia, taget lesion revascularization, cerebral infarction, intracerebral hemorrhage
- Secondary Outcome Measures
Name Time Method 1. all death 2. hospitalization due to heart failure etc 3. renal failure (hemodialysis)