The effects of on the rheologic properties and oxygen transport capacity of red blood cells processed by 3 different types of cell savers, and its effects on microcirculatory blood flow and tissue oxygenation in vivo
Withdrawn
- Conditions
- blood qualitycell saver10011082
- Registration Number
- NL-OMON40462
- Lead Sponsor
- anesthesiologie- onderzoeksbureau
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
Scheduled for OPCABG
age>18 year
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded from participation in this study:
Patients with known hematologic or microvascular disorders. Patients will be excluded intraoperatively when conversion to on-pump coronary artery bypass grafting is necessary or when allogeneic red blood cell transfusion is required
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Primary endpoint of this study is the quality of the washed red blood cells,<br /><br>measured by their deformability and oxygen carrying capacity</p><br>
- Secondary Outcome Measures
Name Time Method <p>the effects of retransfusion of washed cell saver blood in the patient measured<br /><br>by microcirculatory blood flow and tissue oxygenation, and by biochemical<br /><br>markers of organ damage.</p><br>