Selection Criteria for Safe Hepatectomy for Hepatocellular Carcinoma
- Conditions
- HepatectomyHepatecellular CarcinomaCirrhosis
- Interventions
- Procedure: Hepatectomy
- Registration Number
- NCT02056041
- Lead Sponsor
- University of Milan
- Brief Summary
Selection criteria for safe hepatectomy for HCC are not well established. The aim of this study was the validation of the selection criteria for safe hepatectomy for hepatocellular carcinoma.
- Detailed Description
All consecutive patients submitted to hepatectomy for HCC based on the same preoperative selection criteria from our prospectively-maintained liver unit database. Such criteria included the value of bilirubin (BIL), the value of cholinesterases (CHE), the presence of ascites, the presence of esophageal varices, and the rate of residual liver volume.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 336
- any patient with HCC submitted to hepatic resection at our Unit in the established frame time
- any patient with missing data or lost at follow-up
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Hepatectomy for HCC Hepatectomy Patients submitted to surgery for HCC
- Primary Outcome Measures
Name Time Method Safety of surgery for HCC 90 days The primary endpoint was the validation of our selection criteria for safe hepatectomy for HCC in regards to postoperative complications. The role of total bilirubin and cholinesterases was analzyed together with other clinical parameters.
- Secondary Outcome Measures
Name Time Method Score systems HCC 90 days The secondary endpoint was the testing of the most common score systems for HCC, which are the CPT score, the MELD score, and the APRI score.
Trial Locations
- Locations (1)
Humanitas Research Hospital
🇮🇹Rozzano, Milan, Italy