Ventricular Tachycardia in Ischemic Cardiomyopathy; a Combined Endo-Epicardial Ablation Within the First procedure Versus a Stepwise Approach a randomized controlled trial

Recruiting

• Conditions: ventricular tachycardia; 10007521

• Registration Number: NL-OMON53074
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 55

Inclusion Criteria

1. clinical indication for ablation of a monomorphic ventricular tachycardia
referred to one of the participating ablation centers
2. history of ischemic heart disease
3. ICD carrier or ICD implantation planned after the ablation
4. informed written consent

Exclusion Criteria

1. current unstable angina
2. AMI < 30 days or in case of incessant VT < 14 days
3. absence of visualisation of the coronary anatomy (coronary angiogram
/CT-angiogram)
4. significant coronary stenosis approachable for intervention
5. presence of a mobile left ventricle thrombus
5. previous pericarditis
6. presence of mitral/aortic mechanical valves prosthesis; previous coronary
artery bypass graft; any other thoracic surgery that could cause pericardial
adhesions
7. contra-indication for general anaesthesia
8. age below 18 years

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study endpoint is the difference in recurrences of ventricular<br /><br>tachycardia on follow-up - clinical or on ICD interrogation - between the two<br /><br>ablation groups</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Procedure success and safety.</p><br>