Intensive management of infection in high risk leukemia
Not Applicable
- Conditions
- Health Condition 1: C910- Acute lymphoblastic leukemia [ALL]Health Condition 2: C920- Acute myeloblastic leukemia
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
i.AML on intensive induction chemotherapy.
ii.Relapsed acute leukemia on salvage chemotherapy.
Exclusion Criteria
1.Patient not willing to give consent
2.Acute promyelocytic leukemia
3.Patient with documented infection (clinically/microbiologicaly) at the start of Induction/ salvage chemotherapy.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the effect of sepsis bundle based protocol on 30 day mortality among patients with very high risk febrile neutropeniaTimepoint: The data will be collected for the first 30 days of intensive induction treatment
- Secondary Outcome Measures
Name Time Method To study the clinical outcomes (change in MSOFA score at 48 hours ,occurence of septic shock, organ dysfunction, requirement of ventilatory support) in very high risk febrile neutropenia patients managed with sepsis bundle based protocol. <br/ ><br>2.To identify the association of baseline clinical factors, laboratory parameters, profile of infections and pattern of sepsis bundle compliance with 30 day mortality and other clinical outcomes in very high risk febrile neutropenia patients. <br/ ><br>Timepoint: 30days