Crystalloids for AKI in Shock Patients

Not Applicable

• Conditions: Shock
• Interventions: Drug: Fluid resuscitation

• Registration Number: NCT03188614
• Lead Sponsor: Southeast University, China

Brief Summary

Fluid resuscitation is important in shock therapy, but the choice of fluids, especially the choice of crystalloid is under debate. It is said that normal saline is related to hyperchloremia， which might lead to acute kidney injury. Thus the hypothesis of the study is to explicit whether balanced salt solution could reduce the incidence of acute kidney injury when compared with normal saline.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-03-08
• Status Verified: 2017-06
• Study First Submitted QC: 2017-06-14
• Last Update Submitted: 2017-06-14
• Study First Posted: 2017-06-15
• Last Update Posted: 2017-06-15
• Study Start: 2017-08-01
• Primary Completion: 2018-09-01
• Study Completion: 2018-10-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Shock patients

Exclusion Criteria

• History of chronic renal failure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Normal saline group	Fluid resuscitation	Shock patients who resuscitated with normal saline were enrolled between June, 2015-June.2016.
Balanced solution group	Fluid resuscitation	Shock patients who resuscitated with balanced solution were enrolled after June, 2016.

Primary Outcome Measures

Name	Time	Method
Incidence of acute kidney injury	28-day	Diagnosis of acute kidney injury

Secondary Outcome Measures

Name	Time	Method
Usage of renal replacement of therapy	28-day	Usage of CRRT