Efficacy of Tolvaptan in acute heart failure patients with preserved left ventricular ejection fractio
- Conditions
- acute decompensated heart failure
- Registration Number
- JPRN-UMIN000013727
- Lead Sponsor
- Osaka General Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 120
1) Patients with left ventricular ejection fraction>=45%
2) Patients with at least one sign of congestion (edema, pulmonary congestion, pleural effusion, jugular venous distention, orthopnea)
3)Patients who received sufficient explanation, understood it and gave written consent based on their free will, before participating in this study
1) Patients with hypernatremia (Na>147mEq/L)
2) Patients who do not need diuretic therapy because of dehydration
3) Patients with cardiovascular shock
4) Patients with anuria or patients under hemodialysis
5) Patients with acute coronary syndrome
6) Patients with insensitivity to thirst or difficulty in water intake
7) Patients who need mechanical circulatory assist device (IABP?PCPS)
8) Patients with malignant tumor
9) Patients who need temporary pacing because of bradycardia
10) Patients who were judged inappropriate by the principal investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method