Effects of tolvaptan in congestive heart failure patients with renal dysfunctio
Not Applicable
- Conditions
- congestive heart failure
- Registration Number
- JPRN-UMIN000005465
- Lead Sponsor
- Department of cardiology Osaka city university graduate school of medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients who a history of hypersensitivity to tolvaptan 2) Patients with severe hypotention or cardioganic shock 3) Patients with cardiac assist device 4) Patients with dehydration 5) Patients with systolic blood pressure < 90mmHg 6) Patients with serum Na > 147 mEq/L or serum K > 5.5 mEq/L or T- bilirubin > 3.0 mg/dL 7)Patients considered not eligible for the study by the attending doctor due to other reasons
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of change of serum creatinine
- Secondary Outcome Measures
Name Time Method body weight, daily urine volume, congestive findings(leg edema, jugular vein dilatation, pulmonary congestion ), serum sodium, serum potassium, cystatin C