Efficacy and Safety of Tolvaptan in Heart Failure Patients with Renal Impairment and Volume Overload Despite the Standard Treatment with Conventional Diuretics
Not Applicable
- Conditions
- Heart Failure
- Registration Number
- JPRN-UMIN000009201
- Lead Sponsor
- Kanagawa Aquaresis Investigators
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
subjects who already administered injected HF medications (including diueretics, inotropes and vasodilators), and who already use mechanical support (mechanical ventilator such as NIPPV, IABP, PCPS, hemodialysis and hemodiafiltration) / history of allergy against tolvaptan or similar compounds / anuria / subjects who cannot feel thirsty or have difficulty to drink / hyponatremia / subjects who are pregnant or possibly pregnant /subjects who already have tolvaptan at the time of randomization / acute coronary syndrome or those who are planned percutaneous coronary intervention / malignancy / patients who are judged to be inappropriate to this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method