NL-OMON38928
Completed
Not Applicable
Effects of the selective mineralocorticoid receptor antagonist eplerenone on extracellular adenosine formation in humans in vivo - eplerenone and adenosine
niversitair Medisch Centrum Sint Radboud0 sites14 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- blood flow
- Sponsor
- niversitair Medisch Centrum Sint Radboud
- Enrollment
- 14
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy, male, age 18\-40 years, written informed consent
- •(see also chapter 4\.2 (Inclusion criteria) of the protocol)
Exclusion Criteria
- •smoking, history of cardiovascular disease, hypertension, renal dysfunction, serum potassium \> 4\.7 mmol/L
- •(see also chapter 4\.3 (Exclusion criteria) of the protocol)
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Not Applicable
Effects of eplerenone on forearm blood flowhealthy volunteersTherapeutic area: Body processes [G] - Circulatory and Respiratory Physiological Phenomena [G09]EUCTR2013-000189-12-NLniversity Medical Centre Nijmegen
Completed
Phase 2
Effects of mineralocorticoid receptor agonist on intradialytic hypotension: an open-label, randomized crossover studyIntradialytic hypotensionMineralocorticoid receptor agonistTCTR20200128004ampang hospital10
Not yet recruiting
Phase 2
Effects of Mineralocorticoid Receptor Blockade on Metabolism - A Clinical TrialObesityMetabolic and Endocrine - Metabolic disordersDiet and Nutrition - ObesityACTRN12618001958279Dr Moe Thuzar32
Active, not recruiting
Phase 1
Effects of mineralocorticoid receptor stimulation on cognitive bias and social cognition in patients with major depression and healthy controls: what’s the role of NMDA receptors?depressed patients and healthy control subjectsTherapeutic area: Psychiatry and Psychology [F] - Mental Disorders [F03]EUCTR2014-005239-15-DECharité - Universitätsmedizin Berlin232
Completed
Not Applicable
The effect of a mineralocorticoid receptor antagonist eplerenone on morning home BP in drug-resistant hypertensiodrug-resistant morning hypertensionJPRN-UMIN000014186Jichi Medical University School of Medicine100