Colorectal Polyp Discrimination Using High-Definition Narrow Band Imaging
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Colon Polyps
- Sponsor
- Mayo Clinic
- Enrollment
- 556
- Locations
- 1
- Primary Endpoint
- Accuracy of In Vivo determination of colorectal polyps histopathology
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The investigators seek to compare the accuracy of the existing colonoscope model to determine the magnitude of the improvement the investigators can expect in polyp discrimination as neoplastic or non-neoplastic.
Detailed Description
Information will be collected. Images will be taken.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 18 and older
- •Presenting for surveillance, screening or diagnostic colonoscopy
- •Willingness to provide informed consent
Exclusion Criteria
- •Inability to provided informed consent
- •Pregnancy
- •Known inflammatory bowel disease
- •Personal or family history of polyposis or nonpolyposis syndrome
- •Emergency colonoscopy/endoscopy
- •Coagulopathy or thrombocytopenia preventing polypectomy
- •Procedure indication for acute bleeding or active colitis
Outcomes
Primary Outcomes
Accuracy of In Vivo determination of colorectal polyps histopathology
Time Frame: 1 year
Compare accuracy of current colonoscope to improved colonoscope for discrimination of polyps as neoplastic versus non-neoplastic. The accuracies of the two approaches will be compared via logistic regression model with the significance of the difference in the accuracies assessed via generalized estimating equation approach to take account of the possible dependence introduced by inclusion of mulitple polyps per patient.
Secondary Outcomes
- Sensitivity and specificity of In Vivo discrimination of colorectal polyp histopathology in white light and narrow band imaging modes.(1 year)