Effect of a combined natural formula (Royal Jelly + Ginkgo biloba + Panax ginseng) versus placebo on the Mini-Mental State Examination Score (MMSE) in patients with mild cognitive impairment

Not Applicable

Completed

• Conditions: Mild Cognitive Impairment; Forgetfulness; Mental Health - Other mental health disorders; Alternative and Complementary Medicine - Herbal remedies

• Registration Number: ACTRN12613000376741
• Lead Sponsor: Mostafa Yakoot

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-04-09
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

Male or female patients, between 50 and 80 years old, who were complaining of memory impairment or forgetfulness and satisfying the clinical criteria of MCI in the Diagnostic and Statistical Manual of Mental Disorders 4th edition, text revision (DSM-IV-TR) which included: memory complaint, normal activities of daily living, abnormal memory for age and no documented dementia.

Exclusion Criteria

established diagnosis or current treatment for dementia with any drug, any herbal or nutritional supplements except patient with only mild cognitive impairment who stopped treatment for at least one month before enrollment; a baseline MMSE score below 21 or more than 27; or a recent history or current treatment for any specific acquired acute brain injury such as traumatic brain injury (TBI), acute onset stroke, or other acute medical conditions. Patients with a history or current treatment for major depressive or psychotic illnesses as well as critically ill patients or those with severe anemia or vital organ dysfunction hepatic, renal or cardiac failure” were also excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified