Levetiracetam Versus Valproate in Idiopathic Generalized Epilepsy
Completed
- Conditions
- Interventions
- Registration Number
- NCT06393309
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
This study aimed to compare the long-term efficacy and safety of levetiracetam and valproate in treatment of idiopathic generalized epilepsy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 169
Inclusion Criteria
- Diagnosis of juvenile myoclonic epilepsy or generalized tonic-clonic seizure alone
- Regular monotherapy with levetiracetam or sodium valproate
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Exclusion Criteria
- Poor drug adherence
- Pregnancy
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Levetiracetam Levetiracetam Patients with idiopathic generalized epilepsy who were under treatment with levetiracetam Sodium valproate Sodium valproate Patients with idiopathic generalized epilepsy who were under treatment with valproate
- Primary Outcome Measures
Name Time Method Seizure free rate 1 to 5 years The percent of patients who remained seizure free on treatment
Time to first seizure 1 to 5 years The interval between start of treatment and recurrence of seizure
- Secondary Outcome Measures
Name Time Method Retention rate 1 to 5 years The percent of patients who remained on treatment with levetiracetam or valproate
Time to withdrawal 1 to 5 years The interval between start and withdrawal of treatment
Trial Locations
- Locations (1)
Bu Ali Sina Hospital
🇮🇷Sari, Mazandaran, Iran, Islamic Republic of