Effects of Milk Protein Concentrate on Overall Health During Weight Loss in Overweight/Obese Adults

Not Applicable

Completed

• Conditions: High Blood Pressure; Sarcopenia; Metabolic Disease
• Interventions: Other: Energy Restriction

• Registration Number: NCT01692860
• Lead Sponsor: Purdue University

Brief Summary

. The purpose of this study is to examine the effects of eating a larger amount of dairy-based protein on risk factors for metabolic syndrome

Detailed Description

Currently, over 47 million adults in the United States are known to have metabolic syndrome. Metabolic syndrome is comprised of a cluster of conditions including obesity, elevated cholesterol, high blood sugar, and high blood pressure. People with metabolic syndrome have an increased risk for the development of chronic diseases such as cardiovascular disease and diabetes. Recent studies have shown that a build-up of fat in the muscle of overweight and obese people may partially explain the link between metabolic syndrome and the development of chronic diseases. There is evidence to suggest that diets with a higher amount of protein can improve some aspects of metabolic syndrome, including the build-up of fat in muscle. The purpose of this study is to examine the effects of eating a larger amount of dairy-based protein on risk factors for metabolic syndrome.

Study Timeline

• Study Start: 2012-01
• Study First Submitted: 2012-09-21
• Study First Submitted QC: 2012-09-21
• Study First Posted: 2012-09-25
• Primary Completion: 2014-09
• Study Completion: 2015-01
• Status Verified: 2015-11
• Last Update Submitted: 2015-11-03
• Last Update Posted: 2015-11-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

BMI: 25-38 ,male or female; age 35-65 y; weight stable (± 3 kg) during last 3 months; no acute illness; not diabetic, pregnant or lactating; not currently (or within last 3 months) following an exercise or weight loss program; non-smoking; not taking BP medication; not lactose intolerant,

Exclusion Criteria

Subjects will be excluded if baseline protein intake is less than 0.6 or greater than 1.6 g•kg-1•d-1 Subjects will also be excluded if they have any chronic or acute condition which will increase risk of illness or injury during study participation as determined by our study physician such as high BP, high fasting glucose, metabolic syndrome, etc.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
High protein consumption	Energy Restriction	Intervention, energy restriction. This arm has a dietary protein intake of 1.5g/kg/d
Normal protein consumption	Energy Restriction	Intervention, energy restriction. This arm has a dietary protein intake of .8g/kg/d

Primary Outcome Measures

Name	Time	Method
weight loss	20 weeks

Trial Locations

Locations (1)

Purdue University - Stone Hall 700 W State St; 🇺🇸 W Lafayette, Indiana, United States