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Assessment of role of MRI in neonatal encephalopathies

Not Applicable
Conditions
Health Condition 1: P916- Hypoxic ischemic encephalopathy [HIE]
Registration Number
CTRI/2023/07/055568
Lead Sponsor
Kasturba Medical College
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Neonates with diagnosed encephalopathy, or showing any of 3 symptoms- altered mental status, recurrent seizures, abnormal neurological function

Exclusion Criteria

Neonates with severe congenital cardiac/ cerebral anomalies

Known chromosomal anomalies

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ac Cr spectroscopy ratio in specific areas of brain to determine values for categorization by severity of disease <br/ ><br>Fractional Anisotropy values through diffusion tensor imaging to determine extent of involvement of tracts & correlation with clinical outcome <br/ ><br>Timepoint: one year from beginning data collection (baseline) - 31st july 2024 <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
Broad clinical outcomes of child Death or Cerebral Palsy or Delayed development or NormalTimepoint: 2 years from baseline- 31st july 2025
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