Adjuvant Effect of Dexmedetomidine in Ultrasound (USG) Guided Transvers Abdominis Plane Block
- Conditions
- Postoperative Nausea and Vomiting
- Interventions
- Registration Number
- NCT02331563
- Lead Sponsor
- Kırıkkale University
- Brief Summary
A total of 60 adult patients American Society of Anesthesiologists physical status I,II, III were randomized to Group B (n = 30) receiving TAP block with 0.25% bupivacaine and Group D (n = 30) with 0.5 mcg/kg dexmedetomidine added to 0.25 % bupicavaine followed by general anaesthesia. Total local anaesthetic volume was standardised with 20 ml each sides of the abdomen. Hemodynamic responses to surgical incision and intraoperative fentanyl consumption were noted. Visual analog scale (VAS) scores were assessed on the emergence, at 1, 2, 3, 4, 5, 6 and 24 h. Time to first rescue analgesic (when VAS ≥4 cm or on demand), duration of postoperative analgesia, incidence of postoperative nausea-vomiting were also noted.
- Detailed Description
Transversus abdominis plane (TAP) block has been shown to provide postoperative pain relief following various abdominal and inguinal surgeries. The aim of this randomised controlled trial was to assess the effect of transversus abdominis plane (TAP) blocks on opioid requirements and median hospitai stay, postoperative nause and vomitting in patients undergoing laparoscopic cholecystectomy.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
- The patients undergoing laparascopic cholecystectomy
- Story of allergy to bupivacaine and dexmedetomidine
- The surgery preceeded to laparatomy
- Recent abdominal operation history
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 0.5% bupivacaine 0.25 % bupivacaine group 1 receiving TAP block with 0.25% bupivacaine 20 ml for each side of abdomen Bupivacaine is a local anaesthetic agent. transvers abdominis plane block with %0.5 Bustesin which is diluated with normal saline dexmedetomidine added bupivacaine Dexmedetomidine group II receiving TAP block with 0.25% bupivacaine + 0.5 mcg/kg dexmedetomidine each side of abdomen
- Primary Outcome Measures
Name Time Method opioid requirement 24 hr postoperative relief
- Secondary Outcome Measures
Name Time Method postoperative nause and vomiting 24 hrs patient relief
Trial Locations
- Locations (1)
Kırıkkale University School of Medicine Department of Anaesthesiology and Reanimation
🇹🇷Kırıkkale, Yahşihan, Turkey