Feasibility, Acceptability, and Preliminary Effects of ISTDP for Personality Disorders in a Specialized Psychiatric Clinic
- Conditions
- Personality Disorder
- Interventions
- Behavioral: ISTDP
- Registration Number
- NCT06591754
- Lead Sponsor
- Karolinska Institutet
- Brief Summary
The primary objective of this study is to evaluate the feasibility and acceptability of a 25-week combined group and individual therapy program using Intensive Short-Term Dynamic Psychotherapy (ISTDP) for patients diagnosed with personality disorders. The secondary objective is to investigate preliminary effects of the treatment in terms of reducing symtoms of depression, anxiety and emotion regulation difficulties.
- Detailed Description
The investigators vill investigate a 25-week treatment with ISTDP that consists of both weekly group- and individual therapy for patients diagnosed with personality disorder in a psychiatric clinic specialized on depression, anxiety and PTSD. The feasibility and acceptability and preliminary effects will be evaluated using a within-group design with repeated measures and qualitative interviews. Patients will be recruited from the clinic and the main inclusion criteria is that the patient have a personality disorder diagnosis.
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 34
Personality disorder diagnosis (Clinical assessment using STIP-5) Speaks Swedish fluently
Autism or intellectual disability Borderline, antisocial or narcissistic personality disorder diagnosis Need for interpreter Urgent social misery Psychotic disorder High suicidality
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description ISTDP ISTDP ISTDP combined group- and individual therapy
- Primary Outcome Measures
Name Time Method Patients experience of, and satisfaction with, the treatment assessed through qualitative interviews Immediately after treatment completion Patients experience of, and satisfaction with, the treatment assessed through qualitative interviews
Depression symtoms Baseline, weekly throughout treatment, immediately after treatment completion and 6-month follow-up Depression symtoms will be measured with Patient Health Questionnaire (PHQ-9; (Kroenke et al., 2001)
Participants satisfaction with treatment assessed with the Client Satisfaction Questionnaire (CSQ-8) Immediately after treatment completion (25 weeks) Participants satisfaction with treatment assessed with the Client Satisfaction Questionnaire (CSQ-8)
Adverse events related to the treatment From start of treatment up to. 6 month follow up. Adverse events related to the treatment
Number of individual sessions attended during the treatment Throughout the treatment period, up to 25 weeks Number of individual sessions attended during the treatment
Number of group sessions attended during the treatment Throughout the treatment period, up to 25 weeks Number of group sessions attended during the treatment
Number of dropouts Throughout the treatment period, up to 25 weeks Number of dropouts
Total number of sessions attended during the treatment Throughout the treatment period, up to 25 weeks Total number of sessions attended during the treatment
- Secondary Outcome Measures
Name Time Method Fear of negative emotions Change from baseline to post-treatment (25 weeks) and follow up 6 months after treatment. Fear of negative emotion scale (Gilbert et al., 2014) for assessing fear and avoidance of negative feelings.
Anxiety symtoms Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment. Generalized Anxiety Disorder-7 (GAD-7; Spitzer et al., 2006) for assessing anxiety symtoms.
Emotions regulation difficulties Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment. Difficulties in Emotion Regulation Scale (DERS-16; Bjureberg et al., 2016) for assessing difficulties with emotions regulation.
Severity of personality disorder Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment. Levels of Personality Functioning Brief Form (LPFS-BF; Weekers et al., 2019) for assessing degree of personality disorder.
Symtoms of Borderline Personality disorder Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment. Borderline Symtom List (BLS-23; Bohus et al., 2008) for assessing symtoms of Borderline personality disorder.
Quality of life Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment. EuroQol-5D (EQ5D; Balestroni, Gianluigi, \& Bertolotti, 2015) for assessing quality of life.
Working alliance Weekly throughout treatment , up to 25 weeks Session Alliance Inventory (SAI; Falkenström et al., 2015) for assessing the working alliance with the therapist
Emotional activation during therapy Weekly throughout treatment, up to 25 weeks Emotional Experience Self Report (Fisher et al., 2016) for assessing the degree of emotional activation during the session.
Trial Locations
- Locations (1)
Affektiva, ångest och traumaprogrammet, Psykiatri Sydväst
🇸🇪Stockholm, Sweden